diff --git a/test/ruby/test_nomethod_error.rb b/test/ruby/test_nomethod_error.rb
index 6d413e6391..aa2a88b2d8 100644
--- a/test/ruby/test_nomethod_error.rb
+++ b/test/ruby/test_nomethod_error.rb
@@ -106,4 +106,32 @@ class TestNoMethodError < Test::Unit::TestCase
 
     assert_match(/undefined method.+this_method_does_not_exist.+for.+Module/, err.to_s)
   end
+
+  def test_send_forward_raises
+    t = EnvUtil.labeled_class("Test") do
+      def foo(...)
+        forward(...)
+      end
+    end
+    obj = t.new
+    assert_raise(NoMethodError) do
+      obj.foo
+    end
+  end
+
+  # [Bug #21535]
+  def test_send_forward_raises_when_called_through_vcall
+    t = EnvUtil.labeled_class("Test") do
+      def foo(...)
+        forward(...)
+      end
+      def foo_indirect
+        foo # vcall
+      end
+    end
+    obj = t.new
+    assert_raise(NoMethodError) do
+      obj.foo_indirect
+    end
+  end
 end
diff --git a/vm_insnhelper.c b/vm_insnhelper.c
index c9e20e95b4..ac08a00600 100644
--- a/vm_insnhelper.c
+++ b/vm_insnhelper.c
@@ -4185,7 +4185,7 @@ static enum method_missing_reason
 ci_missing_reason(const struct rb_callinfo *ci)
 {
     enum method_missing_reason stat = MISSING_NOENTRY;
-    if (vm_ci_flag(ci) & VM_CALL_VCALL) stat |= MISSING_VCALL;
+    if (vm_ci_flag(ci) & VM_CALL_VCALL && !(vm_ci_flag(ci) & VM_CALL_FORWARDING)) stat |= MISSING_VCALL;
     if (vm_ci_flag(ci) & VM_CALL_FCALL) stat |= MISSING_FCALL;
     if (vm_ci_flag(ci) & VM_CALL_SUPER) stat |= MISSING_SUPER;
     return stat;